Condition education

Chronic Urticaria

Hives lasting six weeks or more, often with no obvious trigger, that can be brought under control.

What it is

Hives that will not go away

Chronic urticaria is the medical term for hives, itchy raised welts, that recur for six weeks or longer. Some people also have deeper swelling called angioedema. In most cases no specific external trigger is found.

More than skin-deep. Chronic urticaria is driven by the immune system's mast cells releasing histamine and other signals. It is usually not an allergy, and it can sometimes be associated with autoimmune conditions.

Signs and symptoms

What it can look like

  • Itchy, raised welts that come and go
  • Welts that move around and fade within a day
  • Deeper swelling of lips, eyes, hands, or feet
  • Symptoms lasting six weeks or longer
  • Flares that disrupt sleep and daily life

Associated conditions

Comorbidities to know

Chronic Urticaria can travel with other conditions, which is why whole-person assessment matters, not just treating the skin.

  • Autoimmune thyroid disease. A recognized association
  • Other autoimmune conditions. Sometimes linked
  • Angioedema. Deeper swelling that can accompany the hives
  • Mental health. Anxiety and low mood, common with unpredictable symptoms

The burden

Why it matters to patients

Unpredictable, itchy welts and swelling interfere with sleep, work, and quality of life, and not knowing when a flare will come adds to the strain.

Care has expanded

There is more help than ever

Chronic urticaria can usually be well controlled with a stepwise approach, and many people improve over time. Care requires accurate diagnosis, severity assessment, and monitoring, with specialty input when standard measures are not enough.

How AURORA helps

Specialty care for chronic urticaria, closer to home

AURORA connects local clinics across rural and remote Alaska to dermatology hubs, so chronic urticaria can be recognized, documented, and managed without a long trip away from home whenever clinically appropriate.

This page is general education, not medical advice. If you have a skin concern, please talk with a clinician. For a severe or rapidly worsening problem, seek local care right away.